PROTEUS-SYNDROME - NEW FINDINGS IN 7 PATIENTS

Seven children with Proteus syndrome (PS) are reported. The majority o f clinical findings coincide with what is reported in the literature. New findings were blue sclerae, telecanthus, epiblepharon, endotropy, hemimegaly of the optic nerve, occipital dysmyelination and compressio n of the corpus callosum, craneosynostosis, decalcification and thinni ng of the cortical layer of long bones, and talipes equinus. The clini cal findings, possible etiology, differential diagnosis, and treatment of PS are discussed.