YEAST ARTIFICIAL CHROMOSOME CONTIG ON MOUSE CHROMOSOME-11 ENCOMPASSING THE NU-LOCUS

Authors
NEHLS M LUNO K SCHORPP M KRAUSE S MATYSIAKSCHOLZE U PROKOP CM HEDRICH HJ BOEHM T
Citation
M. Nehls et al., YEAST ARTIFICIAL CHROMOSOME CONTIG ON MOUSE CHROMOSOME-11 ENCOMPASSING THE NU-LOCUS, European Journal of Immunology, 24(7), 1994, pp. 1721-1723
Citations number
10
Categorie Soggetti
Immunology
Journal title
European Journal of Immunology → ACNP
ISSN journal
00142980
Volume
24
Issue
7
Year of publication
1994
Pages
1721 - 1723
Database
ISI
SICI code
0014-2980(1994)24:7<1721:YACCOM>2.0.ZU;2-I
Abstract
Mutations at the nude locus disrupt the homing process of T cell proge nitor cells to the thymic rudiment, a key aspect of T cell differentia tion. Here,we map the nude locus to a set of overlapping yeast artific ial chromosomes (YAC) clones covering a genetic interval of about 0.5 centi Morgan on mouse chromosome 11. These results provide a suitable starting point to molecularly clone the nude gene.