A four-parameter family of multivariable big q-Jacobi polynomials and
a three-parameter family of multivariable little q-Jacobi polynomials
are introduced. For both families, full orthogonality is proved with t
he help of a second-order q-difference operator which is diagonalized
by the multivariable polynomials. A link is made between the orthogona
lity measures and R. Askey's q-extensions of Seiberg's multidimensiona
l beta-integrals.