This Quick Reference Guide for Clinicians contains recommendations on
the care of patients with unstable angina based on a combination of ev
idence obtained through extensive literature reviews and consensus amo
ng members of an expert panel. Principal conclusions include the follo
wing. (1) Many patients suspected of having unstable angina can be dis
charged home after adequate initial evaluation. (2) Further outpatient
evaluation may be scheduled for up to 72 hours after initial presenta
tion for patients with clinical symptoms of unstable angina judged at
initial evaluation to be at low risk for complications. (3) Patients w
ith acute ischemic heart disease judged to be at intermediate or high
risk of complications should be hospitalized for careful monitoring of
their clinical course. (4) Intravenous thrombolytic therapy should no
t be administered to patients without evidence of ST segment elevation
and acute myocardial infarction. (5) Assessment of prognosis by nonin
vasive testing often aids selection of appropriate therapy. (6) Corona
ry angiography is appropriate for patients judged to be at high risk f
or cardiac complications or death based on their clinical course or re
sults of noninvasive testing. (7) Coronary artery bypass surgery shoul
d be recommended for almost all patients with left main disease and ma
ny patients with three-vessel disease, especially those with left vent
ricular dysfunction. (8) The discharge care plan should include contin
ued monitoring of symptoms; appropriate drug therapy, including aspiri
n; risk-factor modification; and counseling.