In the period between September 1988 and September 1992, 133 patients
(34 males and 99 females; mean age 49 years [range 24-81]) underwent 2
99 extracorporeal shockwave lithotripsy sessions with adjuvant oral bi
le acid therapy. The mean number of extracorporeal shockwave lithotrip
sy sessions was 2.5 (1-7) and the mean number of shock waves 2,817 (75
-4000), while the mean duration per session was 62 minutes (35-210). N
inety-eight patients (73.7%) required intravenous analgo-sedation. At
last follow-up (mean: 17.7 months [2-46]), 37 patients (27.8%) were fr
ee of stones and 30 (22.6%) had undergone cholecystectomy. At 1 year a
fter the first session of extracorporeal shockwave lithotripsy, 51.0%
of the patients with a solitary stone and 8.3% of the patients with 2-
10 stones were free of concrements (p < 0.0001). Fourteen per cent [6/
43] of the patients developed recurrent stones. Major complications co
mprised pancreatitis (n = 4; 3.0%) and acute cholecystitis (n = 1; 0.8
%). Our results reconfirm that extracorporeal shockwave lithotripsy is
safe and moderately effective in selected patients. Because of the wi
de acceptance of the laparoscopic cholecystectomy, extracorporeal shoc
kwave lithotripsy should be restricted to patients at increased surgic
al risk and patients who refuse surgery. In view of the poor results i
n multiple stones, extracorporeal shockwave lithotripsy should be perf
ormed only on solitary stones.