Cf. Streckfus et al., PAROTID FUNCTION AND COMPOSITION OF PAROTID-SALIVA AMONG ELDERLY EDENTULOUS AFRICAN-AMERICAN DIABETICS, Journal of oral pathology & medicine, 23(6), 1994, pp. 277-279
This study examined parotid salivary flow rate and composition in thre
e groups of differently treated diabetics and a control group of non-d
iabetics. The study population was composed of edentulous African-Amer
icans at least 65 years of age. Group A was the control, Group B insul
in-dependent (Regular Iletin, U-100 qd.), Group C controlled by oral m
edication (Tolbutamide, 500 mg qd.), and Group D was diet controlled.
All diabetic patients had serum glucose values under 250 mg/dl. Saliva
ry flow rates, secretory IgA, electrolytes (Na+, Cl-, K+, Ca++) and to
tal protein concentrations were evaluated. The results showed no signi
ficant differences between groups with respect to salivary flow rates,
electrolytes and IgA concentrations. Additionally, all diabetic group
s demonstrated a significantly lower salivary total protein concentrat
ion when compared to the controls. There appears to be no evident decr
ease in salivary flow rate in these three differently controlled diabe
tic groups compared with healthy non-diabetics.