ASYMMETRIC-SYNTHESIS OF THE HYDROXYLAMINO SUGAR OF CALICHEAMICIN

Authors
ROUSH WR FOLLOWS BC
Citation
Wr. Roush et Bc. Follows, ASYMMETRIC-SYNTHESIS OF THE HYDROXYLAMINO SUGAR OF CALICHEAMICIN, Tetrahedron letters, 35(28), 1994, pp. 4935-4938
Citations number
33
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
28
Year of publication
1994
Pages
4935 - 4938
Database
ISI
SICI code
0040-4039(1994)35:28<4935:AOTHSO>2.0.ZU;2-D
Abstract
A stereochemically general procedure for the conversion of 2,3-epoxyal cohols to N-alkoxy oxazolidinones via the DBU promoted cyclizations of 2,3-epoxy-N-alkoxyurethanes has been developed and applied to the fir st asymmetric synthesis of the calicheamicin hydroxylamino sugar, 7.