One hundred and twenty Prim-Holstein cows were randomly assigned to tw
o groups of sixty animals each. In the treated group the animals recei
ved and individual dosis of ergometrine plus serotonine (Sergotonine(T
M)) either within one hour, between 1 to 6 hours or between 6 to 12 ho
urs after calving, by intra-muscular route. Control animals were injec
ted with saline in the same conditions. The placental retention rate w
as significantly lowered in the treated group (10.0 p. 100) as compare
d to the control one (38.3 p. 100) (p < 0.05).