NOTALGIA-PARAESTHETICA - REPORT OF AN ASSOCIATION WITH MACULAR AMYLOIDOSIS

We report three patients with notalgia paraesthetica. In two of our ca ses amyloid deposits were found on skin biopsy. Symptoms had been pres ent in both cases for a number of years. It is well recognized that th e amount of amyloid present in macular amyloid is often very small and difficult to detect. We suggest that many cases of long-standing nota lgia paraesthetica may result in the formation of amyloid, possibly se condary to chronic friction.