ULTRASTRUCTURAL ASPECTS OF VIRUS-REPLICATION IN ONE FATAL CASE AND SEVERAL OTHER ISOLATES FROM A DENGUE TYPE-2 OUTBREAK IN RIO-DE-JANEIRO

Authors
BARTH OM CORTES LMD LAMPE E FARIAS JD
Citation
Om. Barth et al., ULTRASTRUCTURAL ASPECTS OF VIRUS-REPLICATION IN ONE FATAL CASE AND SEVERAL OTHER ISOLATES FROM A DENGUE TYPE-2 OUTBREAK IN RIO-DE-JANEIRO, Memorias do Instituto Oswaldo Cruz, 89(1), 1994, pp. 21-24
Citations number
11
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Memorias do Instituto Oswaldo Cruz → ACNP
ISSN journal
00740276
Volume
89
Issue
1
Year of publication
1994
Pages
21 - 24
Database
ISI
SICI code
0074-0276(1994)89:1<21:UAOVIO>2.0.ZU;2-M
Abstract
Dengue virus replication in mosquito cell cultures was observed by ele ctron microscopy in one fatal and 40 classical isolates from a dengue type 2 outbreak in Rio de Janeiro and compared with the prototype New Guinea C strain. All the Br azilian isolates presented beside the clas sical structured dengue virus particles, fuzzy coated virus-like parti cles, never observed in the referencial New Guinea C virus strain. Mor e numerous DEN-2 virus particles, fuzzy coated virus-like particles, d efective virus particles and smooth membrane structures inside the rou gh endoplasmic reticulum characterized the unique fatal isolate examin ed.