Soft tissue sarcomas are relatively rare in adults, accounting for les
s than one percent of newly diagnosed cancers in the United States eac
h year. However, increased physician awareness of these tumors may lea
d to earlier diagnosis and improved results. The five-year survival ra
te has been increasing, and treatment using a combination of modalitie
s has significantly reduced the number of amputations performed. This
article reviews the clinical presentation, diagnosis. pathology, and t
reatment of soft tissue sarcomas in adults.