PEDIATRIC SOFT-TISSUE SARCOMAS

Soft tissue sarcomas are the sixth most common cancer in children and collectively account for about seven percent of all pediatric cancers. The development of increasingly intensive, multimodality treatment pr otocols for these tumors has led to a steady increase in cure rates fo r these neoplasms, especially for rhabdomyosarcoma, the most common pe diatric soft tissue sarcoma. This article provides an overview of the basic biology, clinical management, and clinical research for pediatri c soft tissue sarcomas.