METABOLIC CHANGES FOLLOWING CORTICAL CONTUSION - RELATIONSHIPS TO EDEMA AND MORPHOLOGICAL-CHANGES

Authors
SUTTON RL HOVDA DA ADELSON PD BENZEL EC BECKER DP
Citation
Rl. Sutton et al., METABOLIC CHANGES FOLLOWING CORTICAL CONTUSION - RELATIONSHIPS TO EDEMA AND MORPHOLOGICAL-CHANGES, Acta neurochirurgica, 1994, pp. 446-448
Citations number
9
Categorie Soggetti
Surgery,Neurosciences
Journal title
Acta neurochirurgica → ACNP
ISSN journal
00016268
Year of publication
1994
Supplement
60
Pages
446 - 448
Database
ISI
SICI code
0001-6268(1994):<446:MCFCC->2.0.ZU;2-O
Abstract
Rats with contusion injury to the right cortex exhibited significant f ormation of edema 6 and 24 hours after injury which resolved by 8 days and was replaced by cavitation necrosis. The contusions produced hype rglycolysis and ischemia in the impacted cortical tissue and underlyin g hippocampus immediately through 30 minutes post-injury. Glucose util ization was depressed throughout the contused cortex and in ipsilatera l subcortical regions, as was blood flow, at chronic (1 and 10 days) p eriods after injury.