ROLE OF LIV-52 IN PROTECTION AGAINST BERYLLIUM INTOXICATION

An ayurvedic medicine, Liv-52, was studied as a prophylactic agent aga inst beryllium-induced toxicity in rats. Administration of beryllium p er se caused severe degenerative and necrotic changes in kidneys, live r, and uterus. Beryllium exposure also reduced glycogen content, activ ities of alkaline phosphatase, succinate-dehydrogenase, and adenosine- triphosphatase in these organs. On the contrary, activities of acid ph osphatase and glucose-6-phosphatase showed marginal increase. Liv-52-p rimed rats exhibited comparatively less marked toxic effects.