NEURODEVELOPMENT IN PEDIATRIC HIV-INFECTION - THE USE OF CAT CLAMS/

Pediatric neuro-AIDS may be the first clinical manifestation of HIV in fection in children born to HN-infected mothers. As part of the neurod evelopmental examination of children, the Clinical Adaptive Test/Clini cal Linguistic and Auditory Milestone Scale (CAT/CLAMS) was investigat ed as a tool for pediatricians to use to monitor the development of ch ildren at risk for HIV infection. The CAT/CLAMS tvas found to detect n eurodevelopmental differences between HIV-infected and uninfected chil dren at 12 and 18 months of age. Good correlations were found between the CAT/CLAMS and concurrently administered Bayley Scales of Infant De velopment. These findings suggest that the CAT/CLAMS should be conside red as a part of the neurodevelopmental examination of children at ris k for pediatric neuro-AIDS.