The purpose of this study is to determine if measures of pulmonary fun
ction are different between endurance trained and nontrained groups of
persons with quadriplegia. After minimum criteria were met, 57 subjec
ts with spinal cord injuries ranging from C5-T1 were surveyed to deter
mine type, duration and intensity of exercise training for the previou
s 6 months. Subjects were assigned to the trained or untrained groups
based on the operational definitions of 'trained' vs 'untrained'. A co
mputerized spirometer was used to test forced vital capacity (FVC), fo
rced mid-expiratory flow (FEF25-75%) and maximum voluntary ventilation
(MVV) as indicators of respiratory muscle strength, airway patency an
d repiratory muscle endurance, respectively. Independent t tests and W
ilcoxon-Mann-Whitney nonparametric tests revealed no significant diffe
rences between the 'trained' and 'untrained' groups for the pulmonary
functions. Correlation analysis revealed a moderate relationship (r =
0.498; p less-than-or-equal-to 0.0001) between a derived continuous va
riable called the weighted training equivalent (WTE) and FVC. Regressi
on analysis revealed that WTE and level of injury accounted for approx
imately 30% of the variance of FVC with WTE contributing 25%. Exercise
training may positively affect FVC in persons with quadriplegia.