E. Fontana et al., FREEZE-DRIED DURA-MATER FOR GUIDED TISSUE REGENERATION IN POST-EXTRACTION DENTAL IMPLANTS - A CLINICAL AND HISTOLOGIC-STUDY, Journal of periodontology, 65(7), 1994, pp. 658-665
SOFT MEMBRANES WERE USED in 69 patients for bone regeneration around i
mplants (blades and screws, submerged and non-submerged) placed into e
xtraction sockets. In about 10% of the patients a prosthetic restorati
on was completed immediately, while in the remaining patients the pros
theses were connected after a healing period of 3 to 6 months; follow-
up ranged from 6 to 30 months. In 22 patients a re-entry procedure was
done to evaluate the membrane and in 4 patients a bone biopsy was tak
en from 3 to 6 months after the placement of the membrane. In all case
s the peri-implant tissues appeared clinically healthy and it was poss
ible to see radiographically that the newly formed bone closely adapte
d to the implants. In most cases it was possible at 6 months re-entry
to see the membrane and detach it from the underlying tissues. There w
as a partial dehiscence of the membrane in only 4% of the cases. After
3 months the tissue under the membrane presented macroscopical featur
es similar to mature bone, and bone biopsies in all cases showed a spo
ngious lamellar bone with a high level of activity and a wide band of
osteoid tissue.