CHRONIC, INFANTILE, NEUROLOGICAL, CUTANEOUS AND ARTICULAR SYNDROME INJAPAN - 2 CASE-REPORTS

We report two Japanese children with chronic, infantile, neurological, cutaneous and articular syndrome. Although the shoulder joint lesion has been rare in the literature of Europe and America, our first case showed overgrowth of the epiphysis in the bilateral shoulder joints. T he second case exhibited severe growth retardation caused by early clo sure of the physis. The influence of GH is irrelevant in this syndrome . The existence of this syndrome in the Orient should be recognized.