THE STRUCTURE OF A C5H4N4O4 SPECIES TRAPPED BY SILYLATION IN PEROXIDASE-MEDIATED URICOLYSIS - A REACTIVE RING-CONTRACTION TO SPIRODIHYDANTOIN

Authors
MODRIC N POJE M GOJMERACIVSIC A
Citation
N. Modric et al., THE STRUCTURE OF A C5H4N4O4 SPECIES TRAPPED BY SILYLATION IN PEROXIDASE-MEDIATED URICOLYSIS - A REACTIVE RING-CONTRACTION TO SPIRODIHYDANTOIN, Bioorganic & medicinal chemistry letters, 4(14), 1994, pp. 1685-1686
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
14
Year of publication
1994
Pages
1685 - 1686
Database
ISI
SICI code
0960-894X(1994)4:14<1685:TSOACS>2.0.ZU;2-K
Abstract
Evidence for the species trapped by trimethylsilylation in peroxidase mediated oxidation of urate (1) having the tetrakis(trimethylsilyl)spi rodihydantoin (4b) structure is provided by its hydrolysis, reaction w ith diazomethane, and actual isolation and identification of tetrameth ylspirodihydantoin (4c).