QUASSINOIDS AS INHIBITORS OF EPSTEIN-BARR-VIRUS EARLY ANTIGEN ACTIVATION

Authors
KUBOTA K FUKAMIYA N TOKUDA H NISHINO H TAGAHARA K LEE KH OKANO M
Citation
K. Kubota et al., QUASSINOIDS AS INHIBITORS OF EPSTEIN-BARR-VIRUS EARLY ANTIGEN ACTIVATION, Cancer letters, 113(1-2), 1997, pp. 165-168
Citations number
9
Categorie Soggetti
Oncology
Journal title
Cancer letters → ACNP
ISSN journal
03043835
Volume
113
Issue
1-2
Year of publication
1997
Pages
165 - 168
Database
ISI
SICI code
0304-3835(1997)113:1-2<165:QAIOEE>2.0.ZU;2-W
Abstract
Short-term in vitro assays for tumor promoters and antitumor promoters (Epstein-Barr virus activation test) were carried out for 14 quassino ids isolated from Ailanthus altissima. Some quassinoids, including ail antinol B, ailantinol C, ailanthone, and shinjulactone A, showed moder ate activity at a molar ratio of 1:100 (TPA/quassinoids), and the resu lts led to the elucidation of structure-activity relationships. (C) 19 97 Elsevier Science Ireland Ltd.