This paper gives a condensed review of studies carried out by the auth
ors in the field of designing electrochemical biosensors for detecting
glucose and phenol in aqueous media. It has been shown that the amper
ometric type sensors operating on the principle of detecting hydrogen
peroxide can be used to analyze glucose in blood. The required identif
ication selectivity is obtained through the specific design of an enzy
me reactor and use of proper materials. The application of biosensors
based on the Clark-type electrode is the most promising for environmen
tal control.