A RISE IN THE INTRACELLULAR CA2+ CONCENTRATION OF ISOLATED RAT SUPRAOPTIC CELLS IN RESPONSE TO OXYTOCIN

Citation
Rc. Lambert et al., A RISE IN THE INTRACELLULAR CA2+ CONCENTRATION OF ISOLATED RAT SUPRAOPTIC CELLS IN RESPONSE TO OXYTOCIN, Journal of physiology, 478(2), 1994, pp. 275-287
Citations number
41
Categorie Soggetti
Physiology
Journal title
ISSN journal
00223751
Volume
478
Issue
2
Year of publication
1994
Pages
275 - 287
Database
ISI
SICI code
0022-3751(1994)478:2<275:ARITIC>2.0.ZU;2-4
Abstract
1. Intracellular Ca2+ concentration ([Ca2+](i)) was monitored in singl e cells isolated from adult rat supraoptic (SO) nuclei. The great majo rity of cells (85%) were neurones and most were immunoreactive to oxyt ocin or to vasopressin (AVP). 2. The resting [Ca2+](i) of the majority (80%) of the neurones remained stable while 20% of the neurones displ ayed spontaneous [Ca2+](i) oscillations which disappeared in low-Ca2(100 nM) EGTA buffer.