METHANESULFENYL TRIFLATE PROMOTED IMINOSULFENYLATION OF AN ALLYLIC TRICHLOROACETIMIDATE - AN EFFICIENT AND STEREOSPECIFIC TOTAL SYNTHESIS OF (-MANNOSTATIN-A())

Authors
LI C FUCHS PL
Citation
C. Li et Pl. Fuchs, METHANESULFENYL TRIFLATE PROMOTED IMINOSULFENYLATION OF AN ALLYLIC TRICHLOROACETIMIDATE - AN EFFICIENT AND STEREOSPECIFIC TOTAL SYNTHESIS OF (-MANNOSTATIN-A()), Tetrahedron letters, 35(29), 1994, pp. 5121-5124
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
29
Year of publication
1994
Pages
5121 - 5124
Database
ISI
SICI code
0040-4039(1994)35:29<5121:MTPIOA>2.0.ZU;2-5
Abstract
The stereospecific synthesis of glycoprotein processing enzyme inhibit or (+) mannostatin A 1 was achieved in ten steps from D-ribonolactone 9 (similar to 39% overall yield). The strategy featured methanesulfeny l triflate mediated intramolecular cyclization of allylic N-sufenylimi date 12.