ERYTHRINA STUDIES .27. PRENYLATED ISOFLAVANONE FROM THE ROOTS OF ERYTHRINA-SIGMOIDEA

Authors
NKENGFACK AE VOUFFO TW FOMUM ZT MEYER M BERGENDORFF O STERNER O
Citation
Ae. Nkengfack et al., ERYTHRINA STUDIES .27. PRENYLATED ISOFLAVANONE FROM THE ROOTS OF ERYTHRINA-SIGMOIDEA, Phytochemistry, 36(4), 1994, pp. 1047-1051
Citations number
19
Categorie Soggetti
Plant Sciences
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
36
Issue
4
Year of publication
1994
Pages
1047 - 1051
Database
ISI
SICI code
0031-9422(1994)36:4<1047:ES.PIF>2.0.ZU;2-O
Abstract
A novel prenylated isoflavanone, sigmoidin I, has been isolated from t he roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin . Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-met hylbut-2-enyl) isoflavanone by means of spectroscopic analyses and che mical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fu migatus and Cryptococcus neoformans, of 50 mg ml(-1).