ISOLATED INTRASPINAL RELAPSE OF NEUROBLASTOMA AFTER AUTOLOGOUS BONE-MARROW TRANSPLANTATION

Authors
FRAPPAZ D BOUFFET E THIESSE P MOTTOLESE C ARTIGES V GRABOIS M COMBARET V DESUZINGES C FAVROT M MENTIGNY MB PHILIP T
Citation
D. Frappaz et al., ISOLATED INTRASPINAL RELAPSE OF NEUROBLASTOMA AFTER AUTOLOGOUS BONE-MARROW TRANSPLANTATION, Pediatric hematology and oncology, 11(4), 1994, pp. 439-443
Citations number
10
Categorie Soggetti
Pediatrics,Oncology,Hematology
Journal title
Pediatric hematology and oncology → ACNP
ISSN journal
08880018
Volume
11
Issue
4
Year of publication
1994
Pages
439 - 443
Database
ISI
SICI code
0888-0018(1994)11:4<439:IIRONA>2.0.ZU;2-S
Abstract
Neuroblastoma may present with spinal cord compression due to dumbbell extension of thoracic or abdominal disease. Isolated intraspinal invo lvement as the sole site of relapse is rare. Two infants with poor-pro gnosis stage IV neuroblastoma presented early after high-dose therapy and autologous bone marrow transplant with isolated spinal relapse her alded by misleading symptoms. The rarity of such isolated relapses is reviewed, and an etiologic hypothesis is proposed.