POTENTIAL OF MACHINE-VISION LIGHT-MICROSCOPY IN TOXICOLOGIC PATHOLOGY

Major developments in machine-vision light microscopy and in reagent c hemistry have led to a renaissance and revolution in the use of the li ght microscope in biology, biotechnology, and medicine. The potential use of this technology in the field of toxicologic pathology is discus sed. It is suggested that a combination of investigating living cells and tissues and fixed samples using the new technologies will lead to understanding mechanisms of toxicity. Examples of the use of the metho ds in basic cell biology and medicine are presented.