R. Achiron et al., PRENATAL ULTRASONOGRAPHIC DIAGNOSIS OF FETAL CEREBRAL VENTRICULITIS ASSOCIATED WITH ASYMPTOMATIC MATERNAL CYTOMEGALOVIRUS-INFECTION, Prenatal diagnosis, 14(7), 1994, pp. 523-526
Cytomegalovirus is the most common cause of congenital viral infection
. In utero infection is usually suspected in patients with growth-reta
rded fetuses or when maternal illness precipitates serological investi
gations. A case is presented where routine ultrasound examination at 3
0 weeks' gestation in an asymptomatic patient demonstrated mild fetal
ventriculomegaly. Transvaginal ultrasound enabled the visualization of
intraventricular adhesions and small periventricular cysts. The suspe
cted diagnosis of in utero cytomegalovirus infection was confirmed by
the presence of IgM antibodies in fetal blood and subsequently by isol
ation of the virus from the infant's urine. The presence of mild fetal
ventriculomegaly should prompt transvaginal brain imaging.