Cadaveric material is often used to guide and validate the interpretat
ion of magnetic resonance imaging (MRI) studies. Direct correlation is
achieved when the cadaver material is imaged and then directly sectio
ned in the plane of the image. Indirect correlation, where the cadaver
ic sections are compared with unrelated in-vivo images, is easier and
more commonly used. Technical difficulties associated with the direct
method include preservation of form and composition of the tissues, an
d the choice of the correct location and plane in which to section the
cadaver. Using an MRI compatible ruler, designed to assist the direct
correlation of MRI and cadaveric sections, we have examined 10 preser
ved (embalmed) cadaveric knees using different MRI sequences on severa
l occasions. Despite these variations, subsequent sectioning of the ca
daveric knees has shown good correlation with the MR images. Of 54 MR
images compared with cadaveric sections, anatomical correlation was ra
ted by independent observers as good or perfect in 47 (87%). This new,
versatile and simple method can make better use of our preserved huma
n cadaveric material and has potentially wide application; we are now
developing it further to assess the technical capabilities of novel im
aging sequences.