NUTRITION AND PROSTATE-CANCER - A PROPOSAL FOR DIETARY INTERVENTION

In this review, we consider the evidence from geographic and metabolic epidemiology and laboratory studies with human prostate cancer cell l ines and animal models that emphasizes the need for the development an d implementation of a dietary intervention trial in prostate cancer pa tients. It is concluded that such a trial should include a reduction i n total fat consumption to 15% of total calories and supplementation o f the diet with selenium, vitamin E, and a soya product. The low-fat i ntervention would provide an appropriate reduction in the intake of an y specifically targeted dietary fatty acid, such as linoleic acid or a lpha-linolenic acid.