CONGENITAL TOXOPLASMOSIS IN TWINS - A CASE-REPORT

We report a case of congenital toxoplasmosis in a twin pregnancy at 21 weeks of gestation. The complete antenatal investigation included ult rasound examination, cordocentesis and amniocentesis. The ultrasonogra phic evaluation showed a distinct morphological aspect confirmed by th e fetal biological profile. The time lag between placental and fetal i nfection, or the immunological fetal responses could explain the varyi ng stages of the fetal disease. This is another case which early demon strates that there may exist a distinct clinical pattern in bichorial pregnancy with varying biological fetal responses. It underlines the i mportance of cordocentesis in the case of maternal toxoplasma seroconv ersion, enabling us to gather a maximum number of biological data for complete appreciation of the fetal status. The information obtained pe rmits a precise adaptation of the medical decision.