P. Gill et al., INDUCTION OF FETAL DEMISE IN ADVANCED PREGNANCY TERMINATIONS - REPORTON A FUNIC POTASSIUM-CHLORIDE PROTOCOL, Fetal diagnosis and therapy, 9(4), 1994, pp. 278-282
Advanced pregnancy termination with uterotonic agents with their inher
ent risk for occurrence of a live birth and surgical evacuation of a f
etus perceived to be vigorous can both be sources of emotional anguish
for women. They argue for offering women an option for induction of f
etal demise prior to uterine evacuation. We report on our experience w
ith 60 pregnancies in which lethal fetal administration of potassium c
hloride was performed prior to evacuation of the uterus. We describe a
double-bolus technique for funic intravascular injection of potassium
chloride to arrest the fetal heart. There were no maternal complicati
ons and the procedure was successful in 86.7% (n = 52) of the cases; o
f the remaining 8 cases, 7 had demise induced by direct fetal cardiac
injection, and a live birth occurred in 1 case.