2 CASES OF ACUTE MYOCARDIAL-INFARCTION ASSOCIATED WITH APLASTIC-ANEMIA DURING TREATMENT WITH ANABOLIC-STEROIDS

Thrombosis is a rare complication in patients with aplastic anemia bec ause of the presence of coincidental thrombocytopenia. We have recentl y treated two cases, a 61-year-old male and a 59-year-old female, with acute myocardial infarction associated with aplastic anemia. Although their platelet counts were lower than normal in spite of treatment wi th anabolic steroids for aplastic anemia, the coronary angiographic fi ndings strongly suggested coronary thrombosis in both cases. Anabolic steroids, which have been commonly used for the treatment of aplastic anemia, are a possible risk factor for coronary thrombosis because the y have an accelerating effect on thrombus formation. We report two ver y rare but clinically important cases.