C. Bustamante et al., INTERACTION OF WATER-SOLUBLE PORPHYRINS WITH SINGLE-STRANDED AND DOUBLE-STRANDED POLYRIBONUCLEOTIDES, Biopolymers, 34(8), 1994, pp. 1099-1104
CD and uv-visible absorption studies with several tetracationic water-
soluble porphyrin derivatives show that some of these species can serv
e as probes to discriminate between A- and B-conformational forms of s
ingle-stranded polynucleotides. It is also observed that these porphyr
ins can participate in the formation of double helices by forming tran
sient intermediate complexes enroute to duplex formation. (C) 1994 Joh
n Wiley & Sons, Inc.