A QUARTZ REACTOR-QUVETTE FOR FLUORESCENT MONITORING OF THE SOLID-PHASE PEPTIDE-SYNTHESIS

Authors
MEDVEDKIN VN PERMYAKOV EA UVERSKY VN GRIPAS AF MITIN YV
Citation
Vn. Medvedkin et al., A QUARTZ REACTOR-QUVETTE FOR FLUORESCENT MONITORING OF THE SOLID-PHASE PEPTIDE-SYNTHESIS, Bioorganiceskaa himia, 20(6), 1994, pp. 635-643
Citations number
43
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
20
Issue
6
Year of publication
1994
Pages
635 - 643
Database
ISI
SICI code
0132-3423(1994)20:6<635:AQRFFM>2.0.ZU;2-5
Abstract
The quartz reactor-quvette for fluorescent monitoring of the solid pha se peptide synthesis consists of a 10 mm diameter quartz tube jackette d in a 14x14 mm orthogonal holder and equipped with chemically inert a dapters. This allows to use the reactor with almost any standard fluor imeter. Details of the construction are presented. Fluorescence spectr a of Fmoc-group, both in solution and on the solid support, are given; effects of concentration quenching of the fluorescence are studied.