In an attempt to better understand congenital subaortic stenosis, we r
eviewed 19 consecutive pediatric patients undergoing surgery for this
problem between 1973 and 1984. Preoperative cardiac catheterization de
monstrated subvalvular stenosis in all patients and associated anomali
es in 11 patients. All patients underwent transaortic resection of the
subaortic membrane. Five patients underwent concurrent additional car
diac procedures. An 8-month-old infant with multiple cardiac anomalies
was the only operative mortality. Follow-up extended to 16 years, wit
h a mean of 6.9 years. In five symptomatic patients, cardiac catheteri
zation revealed a mean systolic pressure gradient of 33.0 +/- 31.94 mm
Hg 24.7 months (mean) after surgery. Two of these patients (11.1 perc
ent of survivors) required reoperation. Twelve of the remaining 13 asy
mptomatic patients underwent echocardiographic follow-up, and 4 were f
ound to have recurrent stenosis with 1 requiring surgery (5.6 percent
of survivors). Our experience shows that transaortic resection of the
subaortic membrane is an acceptable treatment for subvalvular aortic s
tenosis, but is associated with a high incidence of recurrence requiri
ng reoperation (3 of 18 or 16.7 percent). Consequently, it is reasonab
le to consider the role of alternative therapies which may help preven
t recurrence in selected cases.