We describe the first reported case (to our knowledge) of pulmonary gr
anulomatosis caused by aspirated green tea. In this case, we found gra
nulomatous alveolitis with lymph follicles, T lymphocytosis with predo
minantly CD8+ cells in the bronchoalveolar lavage fluids, positive ser
um precipitin and proliferative response of peripheral blood lymphocyt
es to the tea infusion, and efficacy of steroid therapy. These results
indicate that the pathogenesis of the disease was due to both humoral
and cellular immunities to the aspirated green tea.