We report a nearly complete obstruction of the left mainstem bronchus
by a fibrinomyxoid plaque about 12 h after laser resection of scar/gra
nulation tissue at a left bronchial anastomosis 27 days after a left s
ingle lung transplant. The formation of this plaque was associated wit
h respiratory failure. The plaque was removed by grasping the plaque w
ith biopsy forceps inserted through a fiberoptic bronchoscopy that was
placed into the left mainstem bronchus via an endotracheal tube while
the patient was receiving manual ventilation under general anesthesia
. The respiratory failure resolved with removal of the plaque. To our
knowledge, this is a complication that has not been reported previousl
y.