FUNCTIONAL SPECTROSCOPY - LIMITATIONS AND VALUE OF A NEW METHOD FOR EXAMINING BRAIN ACTIVITY USING MRT

Authors
HENNIG J LAUBENBERGER J ERNST T SPECK O FEIFEL E DEUSCHL G LANGER M
Citation
J. Hennig et al., FUNCTIONAL SPECTROSCOPY - LIMITATIONS AND VALUE OF A NEW METHOD FOR EXAMINING BRAIN ACTIVITY USING MRT, RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren, 161(1), 1994, pp. 51-57
Citations number
21
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren → ACNP
ISSN journal
09366652
Volume
161
Issue
1
Year of publication
1994
Pages
51 - 57
Database
ISI
SICI code
0936-6652(1994)161:1<51:FS-LAV>2.0.ZU;2-Z
Abstract
The possibility of examining brain activity by means of localised spec troscopy was studied in relation to its neurological basis. Measuremen ts on 18 normals during optical stimulation showed an improvement in s ignal to noise ratio compared with functional imaging of almost one or der of magnitude. Time dependent measurements during stimulation by a 500 ms light impulse showed definite delay of increased blood flow whe n compared with oxygen utilisation. The excellent signal to noise rati o and the inherent stability of the method permits reliable detection of weak effects such as are caused by finger tapping or electrical sti mulation.