EEG-MANIFESTED BRAIN FUNCTIONAL-STATES AN D AFFECTIVE SYMPTOMS IN FUNCTIONAL-PSYCHOSIS

In 23 patients with the diagnosis of schizoaffective psychosis or delu sional depression, the EEG-activity and reactivity (auditory presentat ion of short sentences and tones) and the psychopathological state (es timated on the syndromatic level of the AMDP [Arbeitsgemeinschaft fur Methodik und Dokumentation in der Psychiatrie] system) were recorded b efore (Day 0) the treatment with a potential neuroleptic and after 20 days of treatment (Day 20). The values of the AMDP affective Syndromes ''manic'' and ''retarded depressive'' were dichotomized. This way we formed for each syndrome a group of high and of low symptomatic patien ts. Patients with high scores in manic syndrome showed at day 0 signif icantly lower alpha-power values, which had a tendency to reversal at day 20. Patients with high scores in retarded depressive syndrome show ed at day 0 a tendency to lower alpha-power values and to higher delta /theta centroids. At day 20, high symptomatic patients in retarded dep ressive syndrome showed significantly higher delta/theta centroids and lower alpha centroids. The calculated correlations supported these fi ndings. The results are discussed within the framework of a model of b rain functioning, that proposes memory-driven and EEG-state dependency of brain information processing.