C. Ruggiero et al., A QUALITATIVE PROCESS THEORY-BASED MODEL OF THE HTV-1 VIRUS-CELL INTERACTION, Computer methods and programs in biomedicine, 43(3-4), 1994, pp. 255-259
We present a qualitative model of the interaction between the HIV-1 vi
rus and the human cell, based on qualitative process theory. This mode
l takes into account a previous qualitative model of the cell growth.
The model presented here can be regarded as a first step for setting u
p a comprehensive model of the HIV-1 virus-cell interaction in which t
he possible points where a drug can attack the virus are evident. The
first simulation trials indicate that the presented model reproduces (
even though in a simplified way) the features of the real behaviour th
at have been considered in the modelling phase. Although our simulatio
n is limited in the knowledge it expresses, it still gives a stimulati
ng opportunity for the evaluation of the criteria chosen as discrimina
nt in the interaction between virus and cell.