INDIAN CHILDHOOD CIRRHOSIS-LIKE LIVER-DISEASE IN AN ARAB CHILD - A BRIEF REPORT

An Arab female child presented with rapidly progressive liver disease, with apparent onset in late infancy and death at 15 months. Microscop y showed panacinar hepatitis, portal and pericellular fibrosis, and di ffuse Mallory bodies in the absence of steatosis or significant choles tasis. Hepatic copper concentration was moderately elevated. Known cau ses of early childhood cirrhosis were excluded. This case meets most o f the established criteria of Indian childhood cirrhosis, yet is unusu al in its occurrence in a child of Arab ancestry and in having a moder ate degree of hepatocellular copper overload.