We have shown that fully differentiated cones in the salmon retina die
as a result of apoptosis (normal cell death). These putative UV cones
begin to disappear from the main retina when the fish is aged 120 day
s and are completely absent at day 220. However, they continue to be p
roduced in the growth zones, ora serrata and ventral fissure, where th
ey are shortlived and never incorporated into the main retina. The dyi
ng cones in the main retina and the growth zones are engulfed by macro
phages and Muller cells.