Fd. Munro et al., RESECTABILITY OF ADVANCED LIVER-TUMORS IN CHILDREN AFTER COMBINATION CHEMOTHERAPY, Annals of the Royal College of Surgeons of England, 76(4), 1994, pp. 253-256
Five patients with locally advanced or metastatic liver tumours were t
reated at the Royal Hospital for Sick Children between 1983 and 1992 b
y preoperative combination chemotherapy and subsequent complete resect
ion of the residual liver tumour. Chemotherapy was generally well tole
rated with few significant adverse effects. Tumour resection was accom
plished by lobectomy in three cases and an extended lobectomy in the r
emaining two. All five children are currently well and free of disease
at a mean follow-up of 36 months.