R. Lastarza et al., 3Q ABERRATION AND MONOSOMY-7 IN ANLL PRESENTING WITH HIGH PLATELET COUNT AND DIABETES-INSIPIDUS, Haematologica, 79(4), 1994, pp. 356-359
Diabetes insipidus and thrombocytosis were presenting symptoms in a ca
se of adult ANLL-M1. Cytogenetic investigations revealed a typical 3q
rearrangement, i.e. inv(3)(q21q26). A subclone with monosomy 7 was als
o found and documented by FISH analysis. Correlations between clinical
/hematological features and cytogenetic/FISH results are discussed.