CENTRAL NEUROCYTOMAS OF THE CERVICAL SPINAL-CORD

Citation
Sb. Tatter et al., CENTRAL NEUROCYTOMAS OF THE CERVICAL SPINAL-CORD, Journal of neurosurgery, 81(2), 1994, pp. 288-293
Citations number
24
Categorie Soggetti
Neurosciences,Surgery
Journal title
ISSN journal
00223085
Volume
81
Issue
2
Year of publication
1994
Pages
288 - 293
Database
ISI
SICI code
0022-3085(1994)81:2<288:CNOTCS>2.0.ZU;2-S
Abstract
Central neurocytoma is a neuronal neoplasm that occurs supratentoriall y in the lateral or third ventricles. The authors report the clinical, neuroradiological, and neuropathological features of two neurocytomas arising in the spinal cord of two men, aged 65 and 49 years. The pati ents presented with progressive neurological deficits referable to the cervical spinal cord. Magnetic resonance imaging revealed isodense in tramedullary spinal cord tumors at the C3-4 level. Both tumors were in itially misdiagnosed as gliomas. In Case 1 the correct diagnosis was m ade after electron microscopy revealed neuronal features. Immunostaini ng in Case 2 revealed that tumor cells were positive for synaptophysin and negative for glial fibrillary acidic protein, strongly indicating a neuronal tumor. It is suggested that this spinal cord neoplasm be i ncluded under the designation ''central neurocytoma.''