CLOMIPRAMINE AMELIORATES ADVENTITIOUS MOVEMENTS AND COMPULSIONS IN PREPUBERTAL BOYS WITH AUTISTIC DISORDER AND SEVERE MENTAL-RETARDATION

Authors
BRASIC JR BARNETT JY KAPLAN D SHEITMAN BB AISEMBERG P LAFARGUE RT KOWALIK S CLARK A TSALTAS MO YOUNG JG
Citation
Jr. Brasic et al., CLOMIPRAMINE AMELIORATES ADVENTITIOUS MOVEMENTS AND COMPULSIONS IN PREPUBERTAL BOYS WITH AUTISTIC DISORDER AND SEVERE MENTAL-RETARDATION, Neurology, 44(7), 1994, pp. 1309-1312
Citations number
19
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
44
Issue
7
Year of publication
1994
Pages
1309 - 1312
Database
ISI
SICI code
0028-3878(1994)44:7<1309:CAAMAC>2.0.ZU;2-S
Abstract
In an open, nonblind clinical trial, clomipramine reduced adventitious movements and compulsions in five previously medicated prepubertal bo ys with autistic disorder and severe mental retardation. Poorly adapte d rating scales, interrater variability, subject heterogeneity, differ ent treatment histories, and environmental stresses confounded the ass essment of treatment effects.