We report three patients (two children and one adult) with Guillain-Ba
rre syndrome and magnetic resonance imaging evidence of gadolinium enh
ancement of the cauda equina and lumbar nerve roots. All three patient
s exhibited symmetric ascending paralysis and areflexia, and two (one
child, one adult) suffered urinary incontinence and retention. Similar
enhancement has been observed in patients with chronic inflammatory d
emyelinating polyneuropathy and suggests proximal nerve inflammation.
Magnetic resonance imaging in Guillain-Barre syndrome and chronic infl
ammatory demyelinating polyneuropathy may have diagnostic utility.