The isomorphism conjecture is investigated for exponential-time and ot
her complexity classes. If one-way functions exist, then we show that
there are one-way functions such that A congruent-to (p)f(A), where A
is a standard complete set for NP or E or NE. If one-way functions exi
st, we also show that there are k-completely creative sets in NP with
one-way productive functions but which are p-isomorphic to standard co
mplete sets. We then present a type of one-way functions whose existen
ce is equivalent to the failure of the isomorphism conjecture for E. F
inally, we show that the isomorphism conjecture holds for E (NE) if an
d only if it holds for EXP (NEXP).