Rc. Cambie et al., BENZANNULATION OF PODOCARPIC ACID-DERIVATIVES VIA DIRECTED ORTHO-METALATION AND LITHIUM-COPPER(I) TRANSMETALATION, Journal of organometallic chemistry, 474(1-2), 1994, pp. 31-41
Three podocarpic acid (1) derivatives have been converted into benzann
ulated derivatives via directed ortho metallation followed by lithium-
copper(I) transmetallation, alkylation and cyclization.