RECURRENT ACUTE INFLAMMATORY DEMYELINATING POLYRADICULITIS AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION

Authors
LIEDTKE W QUABECK K BEELEN DW STRAETEN V SCHAEFER UW
Citation
W. Liedtke et al., RECURRENT ACUTE INFLAMMATORY DEMYELINATING POLYRADICULITIS AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION, Journal of the neurological sciences, 125(1), 1994, pp. 110-111
Citations number
5
Categorie Soggetti
Neurosciences
Journal title
Journal of the neurological sciences → ACNP
ISSN journal
0022510X
Volume
125
Issue
1
Year of publication
1994
Pages
110 - 111
Database
ISI
SICI code
0022-510X(1994)125:1<110:RAIDPA>2.0.ZU;2-J
Abstract
We report a patient who developed recurrent acute inflammatory demyeli nating polyradiculitis (AIDP) receiving immunosuppressive treatment wi th cyclosporin and prednisone for secondary chronic graft versus host disease (GVHD) following allogeneic bone marrow transplantation (BMT) from an unrelated donor for chronic myelogenous leukemia (CML). After the second relapse of AIDP, cyclosporin was discontinued and a rapid, sustained improvement of his neurological deficits occurred. The role of cyclosporin and systemic CMV infection in the pathogenesis of AIDP in this patient are discussed.